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Apollomics Inc.

Industry:   Health Care – Biotechnology: Pharmaceutical Preparations

Stock Symbol:   APLMNASDAQ

 

Animal Usage:   Animal Testing

Our Opinion

Apollomicsis is on the Cruelty Free Investing use of animals list because they conduct pre-clinical tests on animals to evaluate their products’ safety profiles. It’s lead product, vebreltinib (APL-101), was tested for efficacy using preclinical studies that explicitly involved xenograft animal models and patient-derived xenograft models (PDX).

Supporting Evidence:

The company confirms in corporate disclosures that it utilizes animal subjects for product testing.

“By targeting c-MET dysregulation, vebreltinib has demonstrated strong tumor inhibitory effect in a variety of preclinical c-MET dysregulated human gastric, hepatic, pancreatic and lung cancer xenograft animal models and patient-derived xenograft models (PDX).” Read the article for more details

Company Description

Apollomics, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of oncology therapies to harness the immune system and target specific molecular pathways to inhibit cancer. The company’s products portfolio includes Vebreltinib (APL-101), an oral active, highly selective c-Met inhibitor, which is in Phase 2 clinical trials for treatment of non-small cell lung cancer and other solid tumors with MET dysregulation; APL-102, an oral active, small molecule multiple tyrosine kinase inhibitor, which is in a in a Phase 1 clinical trial to inhibit various kinases that are aberrantly activated in cancer cells; and APL-122, a tumor inhibitor candidate, targeting ErbB1/2/4 signaling pathways that is in Phase 1 dose escalation clinical trials to treat cancers within the brain. Its immuno-oncology product candidates comprise APL-501, APL-502, and APL-801. The company was founded in 2015 and is based in Foster City, California.

Company Website: https://www.apollomicsinc.com

Contact:  info@apollomicsinc.com
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