Our Opinion

Vigil Neuroscience Inc. is on the Cruelty-Free Investing usage of animals list because they undertake pre-clinical studies on animals to examine the safety profile of their medications.

Supporting Evidence:

The company mentioned on its website that they use animals for drug testing.

“TREM2 gene mutations (or variants) represent one of the biggest risk factors for Alzheimer’s Disease. Animal model data indicate that therapeutically activating TREM2 can ameliorate neuropathology associated with TREM2 deficiency.” Read the following article

Company Description

Vigil Neuroscience, Inc., a clinical-stage biotechnology company, focuses on developing treatments for rare and common neurodegenerative diseases by restoring the vigilance of microglia, the sentinel immune cells of the brain. Its lead candidate is VGL101, a human monoclonal antibody agonist targeting human triggering receptor expressed on myeloid cells 2 and is in a Phase 2 proof-of-concept trial in patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a rare and fatal neurodegenerative disease. Vigil Neuroscience, Inc. was incorporated in 2020 and is headquartered in Watertown, Massachusetts.

Company Website: https://www.vigilneuro.com